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Home / Primary Antibodies / IHC Antibodies

Anti-WWOX Antibody BHA11301366

SKU : BHA11301366

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Mfr.No.	BS2426
Alternative Names	WW domain-containing oxidoreductase ; Fragile site FRA16D oxidoreductase ; WWOX ; FOR ; WOX1
Antigen	WWOX
Categories	Primary Antibodies
Chromosome Location	16q23.1-q23.2
Clonality	polyclonal
Description	WWOX (WW domain containing oxidoreductase) protein is a candidate tumor suppressor consisting of two WW domains that influence protein-protein interactions, and a short chain dehydrogenase (SDR) domain, that influences sex-steroid metabolism. Modulation of the WWOX gene influences esophageal squamous cell carcinogenesis and tumorigenicity of breast cancer cell lines MDA-MB-435 and T47D. The murine homolog WOX1 localizes in the mitochondria, and contains a mitochondrial targeting sequence mapping within the SDR domain. JNK1 can physically associate with WOX1 and sequester WOX1-dependent apoptosis.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the N-terminual of Human WWOX.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9NZC7
Uniprot	Q9NZC7
Weight	47 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: WWOX (A7) polyclonal antibody detects endogenous levels of WWOX protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301366	BS2426	50µl	$190.44		Add to Cart
BHA11301366	BS2426	100µl	$294.44		Add to Cart

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