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Home / Primary Antibodies

Anti-TNNI1 Antibody

SKU : BHA10903228

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058277
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Clonality	polyclonal
Description	Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal TNNI1 antibody was raised against a peptide from near the N terminal residues of human TNNI1 protein.
Isotype	IgG
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Antigen	TNNI1

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:1,000-1:10,000
Immunohistochemistry: 1:100-500
Optimal dilutions/concentrations should be determined by the end use., IHC ; ELISA

Dilution

ELISA	1:1,000-1:10,000
IHC	1:100-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10903228	Y058277	100 ul	$217.50		Add to Cart

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