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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Tissue Factor/F3 Antibody Picoband®

SKU : BHA21000601

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Mfr.No.	PB9701, PB9701-10ug, PB9701-Biotin, PB9701-Cy3, PB9701-Dylight488, PB9701-Dylight550, PB9701-Dylight594, PB9701-FITC, PB9701-HRP, PB9701-APC, PB9701-PE, PB9701-iFluor647, PB9701-carrier-free
Alternative Names	Tissue factor
Background	Tissue factor also called platelet tissue factor, factor III, or CD142. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alteate splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Tissue Factor/F3 Antibody Picoband® catalog # PB9701. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The (TF:VIIa) complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagat
Host	Rabbit
Immunogen Region	E.coli-derived human Tissue Factor recombinant protein (Position: S33-S295). Human Tissue Factor shares 57.6% and 57.2% amino acid (aa) sequence identity with mouse and rat Tissue Factor, respectively.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tissue factor;TF;Coagulation factor III;Thromboplastin;CD142;F3;
Tissue Specificity	Lung, placenta and pancreas. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P13726
Gene Id	2152
Gene Name	F3
Subcellular Location	Isoform 1: Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA(Cap), 1-5 ug/ml, Human

Reference	1. "Entrez Gene: F3 coagulation factor III (thromboplastin, tissue factor)". 2. Bogdanov VY, Balasubramanian V, Hathcock J, Vele O, Lieb M, Nemerson Y (April 2003). "Alteatively spliced human tissue factor: a circulating, soluble, thrombogenic protein". Nat. Med. 9 (4): 45862. 3. Mackman N (1995). "Regulation of the tissue factor gene". FASEB J. 9 (10): 8839.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000601-1	PB9701	100 ug	-	$370		Add to Cart
BHA21000601-2	PB9701-10ug	10 ug	Sample	$99		Add to Cart
BHA21000601-3	PB9701-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000601-4	PB9701-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000601-5	PB9701-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000601-6	PB9701-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000601-7	PB9701-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000601-8	PB9701-FITC	100 ug	FITC	$570		Add to Cart
BHA21000601-9	PB9701-HRP	100 ug	HRP	$570		Add to Cart
BHA21000601-10	PB9701-APC	100 ug	APC	$670		Add to Cart
BHA21000601-11	PB9701-PE	100 ug	PE	$670		Add to Cart
BHA21000601-12	PB9701-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000601-13	PB9701-carrier-free	100 ug	carrier-free	$370		Add to Cart

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