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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TFPI2 Antibody Picoband®

SKU : BHA21006701

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Mfr.No.	PA1248, PA1248-10ug, PA1248-Biotin, PA1248-Cy3, PA1248-Dylight488, PA1248-Dylight550, PA1248-Dylight594, PA1248-FITC, PA1248-HRP, PA1248-APC, PA1248-PE, PA1248-iFluor647, PA1248-carrier-free
Alternative Names	Tissue factor pathway inhibitor 2
Background	Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-TFPI2 Antibody catalog # PA1248. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human TFPI2.
Isotype	Rabbit IgG
Molecular Weight	51 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tissue factor pathway inhibitor 2;TFPI-2;Placental protein 5;PP5;TFPI2;
Tissue Specificity	Umbilical vein endothelial cells, liver, placenta, heart, pancreas, and mateal serum at advanced pregnancy.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P48307
Gene Name	TFPI2
Sequence	Belongs to the nuclear hormone receptor family. NR1 subfamily.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Sprecher, C. A.; Kisiel, W.; Mathewes, S.; Foster, D. C. : Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor. Proc. Nat. Acad. Sci. 91: 3353-3357, 1994. <br /><br />2. Miyagi, Y.; Yasumitsu, H.; Mizushima, H.; Koshikawa, N.; Matsuda, Y.; Itoh, H.; Hori, T.-A.; Aoki, I.; Misugi, K.; Miyazaki, K. : Cloning of the cDNA encoding mouse PP5/TFPI-2 and mapping of the gene to chromosome 6. DNA and Cell Biology 15: 947-954, 1996.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006701-1	PA1248	-	100 ug	$370		Add to Cart
BHA21006701-2	PA1248-10ug	Sample	10 ug	$99		Add to Cart
BHA21006701-3	PA1248-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006701-4	PA1248-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006701-5	PA1248-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006701-6	PA1248-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006701-7	PA1248-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006701-8	PA1248-FITC	FITC	100 ug	$570		Add to Cart
BHA21006701-9	PA1248-HRP	HRP	100 ug	$570		Add to Cart
BHA21006701-10	PA1248-APC	APC	100 ug	$670		Add to Cart
BHA21006701-11	PA1248-PE	PE	100 ug	$670		Add to Cart
BHA21006701-12	PA1248-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006701-13	PA1248-carrier-free	carrier-free	100 ug	$370		Add to Cart

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