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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Talin 2/TLN2 Antibody Picoband®

SKU : BHA21000860

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Mfr.No.	PB9961, PB9961-10ug, PB9961-Biotin, PB9961-Cy3, PB9961-Dylight488, PB9961-Dylight550, PB9961-Dylight594, PB9961-FITC, PB9961-HRP, PB9961-APC, PB9961-PE, PB9961-iFluor647, PB9961-carrier-free
Alternative Names	Talin-2
Background	Talin 2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Talin 2/TLN2 Antibody Picoband® catalog # PB9961. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Talin 2.
Isotype	Rabbit IgG
Molecular Weight	271 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Talin-2;TLN2;KIAA0320;
Tissue Specificity	Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9Y4G6
Gene Id	83660
Gene Name	TLN2
Subcellular Location	Cell junction, focal adhesion. Cell junction, synapse. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Focal adhesion plaques and synapses.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat

Reference	1. "Entrez Gene: Talin 2". 2. Monkley SJ, Pritchard CA, Critchley DR (Sep 2001). "Analysis of the mammalian talin2 gene TLN2". Biochemical and Biophysical Research Communications 286 (5): 8805. 3. Praekelt U, Kopp PM, Rehm K, Linder S, Bate N, Patel B, Debrand E, Manso AM, Ross RS, Conti F, Zhang MZ, Harris RC, Zent R, Critchley DR, Monkley SJ (Mar 2012). "New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2". European Joual of Cell Biology 91 (3): 18091.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000860-1	PB9961	100 ug	-	$370		Add to Cart
BHA21000860-2	PB9961-10ug	10 ug	Sample	$99		Add to Cart
BHA21000860-3	PB9961-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000860-4	PB9961-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000860-5	PB9961-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000860-6	PB9961-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000860-7	PB9961-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000860-8	PB9961-FITC	100 ug	FITC	$570		Add to Cart
BHA21000860-9	PB9961-HRP	100 ug	HRP	$570		Add to Cart
BHA21000860-10	PB9961-APC	100 ug	APC	$670		Add to Cart
BHA21000860-11	PB9961-PE	100 ug	PE	$670		Add to Cart
BHA21000860-12	PB9961-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000860-13	PB9961-carrier-free	100 ug	carrier-free	$370		Add to Cart

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