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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TAF1 Antibody Picoband®

SKU : BHA21004207

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Mfr.No.	A02151-3, A02151-3-10ug, A02151-3-Biotin, A02151-3-Cy3, A02151-3-Dylight488, A02151-3-Dylight550, A02151-3-Dylight594, A02151-3-FITC, A02151-3-HRP, A02151-3-APC, A02151-3-PE, A02151-3-iFluor647, A02151-3-carrier-free
Alternative Names	mucin 6, oligomeric mucus/gel-forming
Background	Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit (TAFII-250) or TBP-associated factor 250 kDa (p250), is a protein that in humans is encoded by the TAF1 gene. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alteative splicing of this gene results in multiple transcript variants. This gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TAF1 Antibody Picoband® catalog # A02151-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are use
Host	Rabbit
Immunogen Region	E.coli-derived human TAF1 recombinant protein (Position: H1375-D1636).
Isotype	Rabbit IgG
Molecular Weight	250 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Mucin-6; MUC-6; Gastric mucin-6; MUC6
Tissue Specificity	Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P21675
Gene Id	6872
Gene Name	TAF1
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Brown, C. J., Sekiguchi, T., Nishimoto, T., Willard, H. F. Regional localization of CCG1 gene which complements hamster cell cycle mutation BN462 to Xq11-Xq13. Somat. Cell Molec. Genet. 15: 93-96, 1989. <br /><br />2. Christova, R., Oelgeschlager, T. Association of human TFIID-promoter complexes with silenced mitotic chromatin in vivo. Nature Cell Biol. 4: 79-82, 2002. <br /><br />3. Derry, J. M. J., Baard, P. J. Localization of the Ccg1 gene on the mouse X chromosome. (Abstract) Cytogenet. Cell Genet. 51: 988, 1989.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004207-1	A02151-3	-	100 ug	$370		Add to Cart
BHA21004207-2	A02151-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21004207-3	A02151-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004207-4	A02151-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004207-5	A02151-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004207-6	A02151-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004207-7	A02151-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004207-8	A02151-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21004207-9	A02151-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21004207-10	A02151-3-APC	APC	100 ug	$670		Add to Cart
BHA21004207-11	A02151-3-PE	PE	100 ug	$670		Add to Cart
BHA21004207-12	A02151-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004207-13	A02151-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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