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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Syndecan 3/SDC3 Antibody Picoband®

SKU : BHA21007334

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Mfr.No.	PA2133, PA2133-10ug, PA2133-Biotin, PA2133-Cy3, PA2133-Dylight488, PA2133-Dylight550, PA2133-Dylight594, PA2133-FITC, PA2133-HRP, PA2133-APC, PA2133-PE, PA2133-iFluor647, PA2133-carrier-free
Alternative Names	Syndecan-3
Background	Syndecan-3, also called SYND3 is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Syndecan 3/SDC3 Antibody catalog # PA2133. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cell surface proteoglycan that may bear heparan sulfate. May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of mouse Syndecan 3/SDC3, identical to the related rat sequence, and different from the related human sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Syndecan-3;SYND3;Sdc3;Kiaa0468;
Tissue Specificity	Expressed in most tissues. Most abundant in kidney, bone and liver.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q64519
Gene Name	SDC3
Sequence	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Bedt, C., Casaroli-Marano, R. P., Vilaro, S., Reina, M. Cloning and characterization of human syndecan-3. J. Cell. Biol. 82: 246-259, 2001.<br /><br />2. Bobardt, M. D., Saphire, A. C. S., Hung, H.-C., Yu, X., Van der Schueren, B., Zhang, Z., David, G., Gallay, P. A. Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity 18: 27-39, 2003. <br /><br />3. de Witte, L., Bobardt, M., Chatterji, U., Degeest, G., David, G., Geijtenbeek, T. B. H., Gallay, P. Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1.Proc. Nat. Acad. Sci. 104: 19464-19469, 2007. <br /><br />4. Ha, E., Kim, M.-J., Choi, B.-K., Rho, J.-J., Oh, D.-J., Rho, T.-H., Kim, K.-H., Lee, H. J., Shin, D.-H., Yim, S. V., Baik, H. H., Chung, J.-H., Kim, J. W. Positive association of obesity with single nucleotide polymorphisms of syndecan 3 in the Korean population. J. Clin. Endocr. Metab. 91: 5095-5099, 2006. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007334-1	PA2133	-	100 ug	$370		Add to Cart
BHA21007334-2	PA2133-10ug	Sample	10 ug	$99		Add to Cart
BHA21007334-3	PA2133-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007334-4	PA2133-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007334-5	PA2133-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007334-6	PA2133-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007334-7	PA2133-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007334-8	PA2133-FITC	FITC	100 ug	$570		Add to Cart
BHA21007334-9	PA2133-HRP	HRP	100 ug	$570		Add to Cart
BHA21007334-10	PA2133-APC	APC	100 ug	$670		Add to Cart
BHA21007334-11	PA2133-PE	PE	100 ug	$670		Add to Cart
BHA21007334-12	PA2133-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007334-13	PA2133-carrier-free	carrier-free	100 ug	$370		Add to Cart

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