Anti-SMAD9/SMAD5/SMAD1 Antibody BHA11301413

Mfr.No.	BS2486
Alternative Names	Mothers against decapentaplegic homolog 1 ; MAD homolog 1 ; Mothers against DPP homolog 1 ; JV4-1 ; Mad-related protein 1 ; SMAD family member 1 ; SMAD 1 ; Smad1 ; hSMAD1 ; Transforming growth factor-beta-signaling protein 1 ; BSP-1 ; SMAD1 ; BSP1 ; MADH1 ; MADR1 ; Mothers against decapentaplegic homolog 5 ; MAD homolog 5 ; Mothers against DPP homolog 5 ; V5-1 ; SMAD family member 5 ; SMAD 5 ; Smad5 ; hSmad5 ; SMAD5 ; MADH5 ; Mothers against decapentaplegic homolog 9 ; MAD homolog 9 ; Mothers against DPP homolog 9 ; Madh6 ; SMAD family member 9 ; SMAD 9 ; Smad9 ; SMAD9 ; MADH6 ; MADH9
Antigen	SMAD9/SMAD5/SMAD1
Categories	Primary Antibodies
Clonality	polyclonal
Description	Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MadH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the N-terminal of Human Smad1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q15797/Q99717/O15198
Uniprot	Q15797/Q99717/O15198
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Smad1/5/9 (Q22) polyclonal antibody detects endogenous levels of Smad1/5/9 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.