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Home / Primary Antibodies / IHC Antibodies

Anti-SLC2A4 Antibody BHA11302126

SKU : BHA11302126

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Mfr.No.	BS3680
Alternative Names	Solute carrier family 2 ; facilitated glucose transporter member 4 ; Glucose transporter type 4 ; insulin-responsive ; GLUT-4 ; GLUT4 ; SLC2A4
Categories	Primary Antibodies
Chromosome Location	17p13.1
Clonality	polyclonal
Description	In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut1 and Glut4 are twelve pass transmembrane proteins (12TM) whose carboxy-termini may dictate their cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 250-300 of Human Glut 4.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P14672
Uniprot	P14672
Weight	45 to 60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: Glut4 (R271) polyclonal antibody detects endogenous levels of Glut4 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302126	BS3680	50µl	$190.44		Add to Cart
BHA11302126	BS3680	100µl	$294.44		Add to Cart

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