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Home / Primary Antibodies / Recombinant Antibodies

Anti-SLAMF7 Antibody BHA11307889

SKU : BHA11307889

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Mfr.No.	BS7859
Alternative Names	19A ; CD319 ; CRACC ; CS1 ; SLAMF7
Antigen	SLAMF7
Categories	Primary Antibodies
Chromosome Location	1q23.3
Clonality	polyclonal
Description	CS1, also known as novel Ly9, SLAMF7, CD319, 19A24 or CRACC, is a homophilic cell surface receptor. It is a member of the SLAM (signaling lymphocytic activation molecule) family of receptors expressed on natural killer (NK) cells, T cells and stimulated B cells. CS1 contains immunoreceptor tyrosine-based switch motifs in its cytoplasmic domain but, unlike other SLAM receptors, it does not recruit SAP (SLAM-associated protein). In humans, CS1 activates NK cells through an EAT-2-mediated pathway that is SAP-independent. CS1 recruits and associates with EAT-2, a protein closely related to SAP. EAT-2 induces phosphorylation of CS1 which then, upon ligand binding, activates downstream cytotoxicity effectors PLCγ and PI 3-kinase. In mice, the EAT-2 association with CS1 has an inhibitory effect on the activation of NK cells.
Host	Rabbit
Immunogen	Recombinant full length Human CD319.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9NQ25
Uniprot	Q9NQ25
Weight	37 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: CD319 polyclonal antibody detects endogenous levels of CD319 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307889	BS7859	50µl	$234.89		Add to Cart
BHA11307889	BS7859	100µl	$368.22		Add to Cart

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