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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ROBO4 Antibody Picoband®

SKU : BHA21005403

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Mfr.No.	A04479-2, A04479-2-10ug, A04479-2-Biotin, A04479-2-Cy3, A04479-2-Dylight488, A04479-2-Dylight550, A04479-2-Dylight594, A04479-2-FITC, A04479-2-HRP, A04479-2-APC, A04479-2-PE, A04479-2-iFluor647, A04479-2-carrier-free
Alternative Names	Integrin alpha-L
Background	Roundabout homolog 4 is a protein that in humans is encoded by the ROBO4 gene. Predicted to enable cell-cell adhesion mediator activity. Involved in angiogenesis and establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ROBO4 Antibody Picoband® catalog # A04479-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes an
Host	Rabbit
Immunogen Region	E.coli-derived human ROBO4 recombinant protein (Position: D108-A933).
Isotype	Rabbit IgG
Molecular Weight	107 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Integrin alpha-L;CD11 antigen-like family member A;Leukocyte adhesion glycoprotein LFA-1 alpha chain;LFA-1A;Leukocyte function-associated molecule 1 alpha chain;CD11a;ITGAL;CD11A;
Tissue Specificity	Leukocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8WZ75
Gene Id	54538
Gene Name	ROBO4
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bedell, V. M., Yeo, S.-Y., Park, K. W., Chung, J., Seth, P., Shivalingappa, V., Zhao, J., Obara, T., Sukhatme, V. P., Drummond, I. A., Li, D. Y., Ramchandran, R. roundabout4 is essential for angiogenesis in vivo. Proc. Nat. Acad. Sci. 102: 6373-6378, 2005. <br /><br />2. Gould, R. A., Aziz, H., Woods, C. E., Seman-Senderos, M. A., Sparks, E., Preuss, C., Wunnemann, F., Bedja, D., Moats, C. R., McClymont, S. A., Rose, R., Sobreira, N., and 33 others. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Nature Genet. 51: 42-50, 2019. <br /><br />3. Huminiecki, L., Go, M., Suchting, S., Poulsom, R., Bicknell, R. Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis. Genomics 79: 547-552, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005403-1	A04479-2	-	100 ug	$370		Add to Cart
BHA21005403-2	A04479-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21005403-3	A04479-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005403-4	A04479-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005403-5	A04479-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005403-6	A04479-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005403-7	A04479-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005403-8	A04479-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21005403-9	A04479-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21005403-10	A04479-2-APC	APC	100 ug	$670		Add to Cart
BHA21005403-11	A04479-2-PE	PE	100 ug	$670		Add to Cart
BHA21005403-12	A04479-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005403-13	A04479-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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