Anti-RAD51B Antibody BHA11301445

Mfr.No.	BS2542
Alternative Names	DNA repair protein RAD51 homolog 2 ; R51H2 ; RAD51 homolog B ; Rad51B ; RAD51-like protein 1 ; RAD51B ; RAD51L1 ; REC2
Antigen	RAD51B
Categories	Primary Antibodies
Chromosome Location	14q24.1
Clonality	polyclonal
Description	The DNA repair proteins Rad50, Rad51A-D, Rad52 and Rad54 A and B are key components of the double-strand break repair pathway (DSBR). The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks to promote error-free repair. Human Rad51 protein assembles on a DNA molecule through cooperative binding and forms a long filament for homologous recombination. In addition to Rad51 protein, five paralogs have been identified in vertebrates, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3. Rad51B is a widely expressed protein that is involved in the repair of double-stranded DNA breaks that can arise during DNA replication. It can form a dimer with Rad51C and this complex shows single-stranded DNAdependent ATPase activity.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 201-250 of Human Rad51B.
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Rad51B (G226) polyclonal antibody detects endogenous levels of Rad51B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.