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Home / Primary Antibodies / IHC Antibodies

Anti-PXN Antibody BHA11302044

SKU : BHA11302044

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Mfr.No.	BS3585
Alternative Names	PXN
Antigen	PXN
Categories	Primary Antibodies
Chromosome Location	12q24.23
Clonality	polyclonal
Description	Paxillin is a focal adhesion phosphoprotein that is localized to the cytoskeleton. FAK phosphorylates paxillin specifically on Tyr 118 in vitro. However, FAK phosphorylation does not seem to be required for the recruitment of paxillin to cell adhesion sites. Paxillin may play a role in signal transduction, regulation of cell morphology and the recruitment of structural and signaling molecules to focal adhesions. It has been shown that the amount of paxillin is reduced in mitotic cells by proteolytic downregulation and that paxillin is alternatively phosphorylated on serine rather than on tyrosine and serine during mitosis.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids N-terminus of Human Paxillin.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P49023
Uniprot	P49023
Weight	65 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Paxillin (L25) polyclonal antibody detects endogenous levels of Paxillin protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302044	BS3585	50µl	$190.44		Add to Cart
BHA11302044	BS3585	100µl	$294.44		Add to Cart

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