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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PU.1

SKU : BHA15100307

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BioGenex Laboratories

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Mfr.No.	AN843-5M
Clonality	Monoclonal
Description	PU.1 is a transcription factor of ETS (E26 transformation-specific) family; it is required for hematopoiesis. It has a critical role in differentiation of normal myeloid progeny, and regulates the immunoglobulin gene expression and other genes that are significant for B cell development. PU.1 stains B lymphocyte in germinal center and mantle B cell, but not plasma cell. It labels many types of B cell lymphoma including mantle cell lymphoma, but it is not expressed in classical Hodgkin lymphoma (cHL). The lack of transcription factor PU.1 protein expression in cHL, a lympho- proliferative disease of predominantly B-cell origin, likely contributes to the lack of immunoglobulin expression and incomplete B-cell phenotype characteristic of the Reed-Sternberg cells in cHL.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	EP18
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN843-5M	AN843-5M	6 mL	$339		Add to Cart
AN843-10M	AN843-10M	100 tests - i6000	$608		Add to Cart
AY843-50D	AY843-50D	50 tests - Xmatrx	$361		Add to Cart
AY843-YCD	AY843-YCD	160 tests - Xmatrx	$973		Add to Cart
NU843-UC	NU843-UC	1ml Conc	$489		Add to Cart
NU843-5UC	NU843-5UC	0.5ml Conc	$339		Add to Cart

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