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Home / Primary Antibodies / IHC Antibodies

Anti-PTH1R Antibody BHA11301557

SKU : BHA11301557

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Mfr.No.	BS2710
Alternative Names	Parathyroid hormone/parathyroid hormone-related peptide receptor ; PTH/PTHrP type I receptor ; PTH/PTHr receptor ; Parathyroid hormone 1 receptor ; PTH1 receptor ; PTH1R ; PTHR ; PTHR1
Antigen	PTH1R
Categories	Primary Antibodies
Chromosome Location	3p21.31
Clonality	polyclonal
Description	Parathyroid hormone (PTH), which is also designated parathyrin, is an 84 amino acid single chain peptide that functions to regulate calcium metabolism by raising blood levels of calcium through various mechanisms. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino-terminus of the molecule. The gene encoding PTH maps to human chromosome 11p15.3-p15.1. Parathyroid hormone-related protein (PTH-rP) is an autocrine factor that is structurally related to PTH yet, unlike PTH, which is synthesized only by the parathyroid cells, PTH-rP is synthesized by several cell types. PTH-rP regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Isolated from the culture medium of a human lung cancer cell line, PTH-rP produces PTH-like effects that are characterized as humoral hypercalcemia of malignancy.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 150-200 of Human PTH.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q03431
Uniprot	Q03431
Weight	52, 66kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PTH/PTHrP-R (L187) polyclonal antibody detects endogenous levels of PTH/PTHrP-R protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301557	BS2710	50µl	$190.44		Add to Cart
BHA11301557	BS2710	100µl	$294.44		Add to Cart

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