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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PIK3R5 Antibody Picoband®

SKU : BHA21005788

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Mfr.No.	A02827-2, A02827-2-10ug, A02827-2-Biotin, A02827-2-Cy3, A02827-2-Dylight488, A02827-2-Dylight550, A02827-2-Dylight594, A02827-2-FITC, A02827-2-HRP, A02827-2-APC, A02827-2-PE, A02827-2-iFluor647, A02827-2-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alteatively spliced transcript variants encoding two distinct isoforms have been found.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-PIK3R5 Antibody Picoband® catalog # A02827-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human PIK3R5 recombinant protein (Position: E170-L864). Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.
Isotype	IgG
Molecular Weight	97 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8WYR1
Gene Id	23533
Gene Name	PIK3R5
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Al Tassan, N., Khalil, D., Shinwari, J., Al Sharif, L., Bavi, P., Abduljaleel, Z., Abu Dhaim, N., Magrashi, A., Bobis, S., Ahmed, H., AlAhmed, S., Bohlega, S. A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia. Hum. Mutat. 33: 351-354, 2012.<br /><br />2. Brock, C., Schaefer, M., Reusch, H. P., Czupalla, C., Michalke, M., Spicher, K., Schultz, G., Nuberg, B. Roles of G-beta-gamma in membrane recruitment and activation of p110-gamma/p101 phosphoinositide 3-kinase gamma. J. Cell Biol. 160: 89-99, 2003.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005788-1	A02827-2	-	100 ug	$370		Add to Cart
BHA21005788-2	A02827-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21005788-3	A02827-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005788-4	A02827-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005788-5	A02827-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005788-6	A02827-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005788-7	A02827-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005788-8	A02827-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21005788-9	A02827-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21005788-10	A02827-2-APC	APC	100 ug	$670		Add to Cart
BHA21005788-11	A02827-2-PE	PE	100 ug	$670		Add to Cart
BHA21005788-12	A02827-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005788-13	A02827-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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