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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PIK3AP1 Antibody Picoband®

SKU : BHA21005786

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Mfr.No.	A08114, A08114-10ug, A08114-Biotin, A08114-Cy3, A08114-Dylight488, A08114-Dylight550, A08114-Dylight594, A08114-FITC, A08114-HRP, A08114-APC, A08114-PE, A08114-iFluor647, A08114-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Phosphoinositide 3-kinase adapter protein 1 is an enzyme that in humans is encoded by the PIK3AP1 gene. BCAP (B cell adaptor for phosphoinositide 3-kinase (PI3K)), also known as PI3KAP1, participates in linking the B cell antigen receptor (BCR) with the PI3K pathway. Tyrosine phosphorylation of BCAP by BCR-associated protein tyrosine kinases, such as Syk and Btk, generates binding sites for the p85 subunit of PI3K, resulting in activation of the PI3K pathway. Human and mouse BCAP contain 3 YXXM SH2 binding motifs for interaction with PI3K. BCAP null mice have deficient immune function, with B cells that exhibit enhanced apoptosis.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-PIK3AP1 Antibody Picoband® catalog # A08114. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human PIK3AP1 recombinant protein (Position: H78-R583). Human PIK3AP1 shares 83.8% amino acid (aa) sequence identity with mouse PIK3AP1.
Isotype	IgG
Molecular Weight	90 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q6ZUJ8
Gene Id	118788
Gene Name	PIK3AP1
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Okada, T., Maeda, A., Iwamatsu, A., Gotoh, K., Kurosaki, T. BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity 13: 817-827, 2000. <br /><br />2. Yamazaki, T., Kurosaki, T. Contribution of BCAP to maintenance of mature B cells through c-Rel. Nature Immun. 4: 780-786, 2003. <br /><br />3. Yamazaki, T., Takeda, K., Gotoh, K., Takeshima, H., Akira, S., Kurosaki, T. Essential immunoregulatory role for BCAP in B cell development and function. J. Exp. Med. 195: 535-545, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005786-1	A08114	-	100 ug	$370		Add to Cart
BHA21005786-2	A08114-10ug	Sample	10 ug	$99		Add to Cart
BHA21005786-3	A08114-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005786-4	A08114-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005786-5	A08114-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005786-6	A08114-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005786-7	A08114-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005786-8	A08114-FITC	FITC	100 ug	$570		Add to Cart
BHA21005786-9	A08114-HRP	HRP	100 ug	$570		Add to Cart
BHA21005786-10	A08114-APC	APC	100 ug	$670		Add to Cart
BHA21005786-11	A08114-PE	PE	100 ug	$670		Add to Cart
BHA21005786-12	A08114-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005786-13	A08114-carrier-free	carrier-free	100 ug	$370		Add to Cart

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