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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Phosphoglycerate kinase 1 PGK1 Antibody Picoband®

SKU : BHA21007260

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Mfr.No.	PA2045, PA2045-10ug, PA2045-Biotin, PA2045-Cy3, PA2045-Dylight488, PA2045-Dylight550, PA2045-Dylight594, PA2045-FITC, PA2045-HRP, PA2045-APC, PA2045-PE, PA2045-iFluor647, PA2045-carrier-free
Alternative Names	Phosphoglycerate kinase 1
Background	PGK1 (Phosphoglycerate Kinase 1), also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. And the encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Phosphoglycerate kinase 1 PGK1 Antibody catalog # PA2045. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human PGK1, identical to the related rat and mouse sequences.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Phosphoglycerate kinase 1;2.7.2.3;Cell migration-inducing gene 10 protein;Primer recognition protein 2;PRP 2;PGK1;PGKA;MIG10, OK/SW-cl.110;
Tissue Specificity	Expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P00558
Gene Name	PGK1
Sequence	Belongs to the phosphoglycerate kinase family.
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. "Entrez Gene: PGK1 phosphoglycerate kinase 1".<br /><br />2. Michelson AM, Markham AF, Orkin SH (May 1983). "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase". Proc Natl Acad Sci U S A 80 (2): 4726.<br /><br />3. Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD (May 1985). "Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase)". Gene 32 (3): 40917.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007260-1	PA2045	-	100 ug	$370		Add to Cart
BHA21007260-2	PA2045-10ug	Sample	10 ug	$99		Add to Cart
BHA21007260-3	PA2045-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007260-4	PA2045-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007260-5	PA2045-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007260-6	PA2045-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007260-7	PA2045-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007260-8	PA2045-FITC	FITC	100 ug	$570		Add to Cart
BHA21007260-9	PA2045-HRP	HRP	100 ug	$570		Add to Cart
BHA21007260-10	PA2045-APC	APC	100 ug	$670		Add to Cart
BHA21007260-11	PA2045-PE	PE	100 ug	$670		Add to Cart
BHA21007260-12	PA2045-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007260-13	PA2045-carrier-free	carrier-free	100 ug	$370		Add to Cart

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