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Home / Primary Antibodies / IHC Antibodies

Anti-PHF1 Antibody BHA11301387

SKU : BHA11301387

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Mfr.No.	BS2453
Alternative Names	PHD finger protein 1 ; Protein PHF1 ; hPHF1 ; Polycomb-like protein 1 ; hPCl1 ; PHF1 ; PCL1
Antigen	PHF1
Categories	Primary Antibodies
Chromosome Location	6p21.32
Clonality	polyclonal
Description	PHF1 (PHD protein finger 1), also known as polycomb-like protein 1 or hPCI1, is a 567 amino acid member of the PHD finger protein family. Members of the PHD finger protein family function as transcriptional regulators that affect gene expression by modulating chromatin structure. With a subcellular localization to the nucleus, PHF1 is widely expressed in tissues, with high expression in pancreas, heart and skeletal muscle and low expression in liver, lung, kidney, brain and placenta. PHF1 contains 2 PHD-type zinc finger domains, which may contribute to the transcriptional activity of PHF1. PHF1 is thought to interact with ENX-1, a component of PRC2 (polycomb repressive complex 2), increasing the gene silencing activity of PRC2. PHF1 exists as two isoforms produced by alternative splicing.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 361-410 of Human PHF1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O43189
Uniprot	O43189
Weight	; 62 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PHF1 (K381) polyclonal antibody detects endogenous levels of PHF1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301387	BS2453	50µl	$190.44		Add to Cart
BHA11301387	BS2453	100µl	$294.44		Add to Cart

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