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Home / Antibodies

Anti-PEG10 Polyclonal Antibody

SKU : BHA13601851-401427

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Beijing Solarbio Science & Technology Co., Ltd.

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Mfr.No.	K003486P
Alternative Names	EDR ; HB-1 ; MEF3L ; Mar2 ; Mart2 ; RGAG3 ; RTL2 ; SIRH1
Background	This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis. Overexpression of this gene has been associated with several malignancies, such as hepatocellular carcinoma and B-cell lymphocytic leukemia. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. Additional isoforms resulting from alternatively spliced transcript variants, and use of upstream non-AUG (CUG) start codon have been reported for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit(Rb)
Immunogen	Recombinant protein of human PEG10
Isotype	IgG
Molecular Weight	80kDa
Promotion	By one Solarbio antibody to get same size loading control/tag antibody for free. Click here to read more
Reactivity	Human
Subcellular Location	Cytoplasm Nucleus

Swissprot	Q86TG7
Gene Id	23089
Gene Name	PEG10

Purification	Affinity purification
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications	WB
Dilution	WB 1:200-2000.

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SKU	Supplier No.	Size	Your price	Quantity
BHA13601851-401427	K003486P	50µl	$278.89		Add to Cart
BHA13601851-401427	K003486P	100µl	$356.67		Add to Cart

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