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Home / Primary Antibodies / IHC Antibodies

Anti-PDGFRB Antibody BHA11300894

SKU : BHA11300894

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Mfr.No.	BS1763
Alternative Names	Platelet-derived growth factor receptor beta ; PDGF-R-beta ; PDGFR-beta ; Beta platelet-derived growth factor receptor ; Beta-type platelet-derived growth factor receptor ; CD140 antigen-like family member B ; Platelet-derived growth factor receptor 1 ; PDGFR-1 ; CD140b ; PDGFRB ; PDGFR ; PDGFR1 ; PDGFRβ
Categories	Primary Antibodies
Chromosome Location	5q32
Clonality	polyclonal
Description	Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 971-1020 of Human PDGFR-β.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P09619
Uniprot	P09619
Weight	124, 190 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PDGFR-β (D1003) polyclonal antibody detects endogenous levels of PDGFR-β protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300894	BS1763	50µl	$190.44		Add to Cart
BHA11300894	BS1763	100µl	$294.44		Add to Cart

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