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Home / Primary Antibodies / IHC Antibodies

Anti-PDE4D Antibody BHA11300727

SKU : BHA11300727

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Mfr.No.	BS1572
Alternative Names	cAMP-specific 3',5'-cyclic phosphodiesterase 4D ; DPDE3 ; PDE43 ; PDE4D ; DPDE3
Antigen	PDE4D
Categories	Primary Antibodies
Chromosome Location	5q11.2-q12.1
Clonality	polyclonal
Description	Phosphodiesterases (PDE) hydrolyze cAMP to 5’AMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4D gene maps to chromosome 5q12.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 30-70 Human PDE4D.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q08499
Uniprot	Q08499
Weight	91 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: PDE4D (H47) polyclonal antibody detects endogenous levels of PDE4D protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300727	BS1572	50µl	$190.44		Add to Cart
BHA11300727	BS1572	100µl	$294.44		Add to Cart

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