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Home / Primary Antibodies / Polyclonal Antibodies

Anti-p70 S6K/RPS6KB1 Antibody Picoband®

SKU : BHA21006385

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Mfr.No.	A01475-3, A01475-3-10ug, A01475-3-Biotin, A01475-3-Cy3, A01475-3-Dylight488, A01475-3-Dylight550, A01475-3-Dylight594, A01475-3-FITC, A01475-3-HRP, A01475-3-APC, A01475-3-PE, A01475-3-iFluor647, A01475-3-carrier-free
Background	This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alteatively spliced transcript variants have been observed. The use of alteative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Clonality	Polyclonal
Description	Boster Bio Anti-p70 S6K/RPS6KB1 Antibody Picoband® catalog # A01475-3. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human p70 S6K/RPS6KB1 recombinant protein (Position: R7-Q500). Human RPS6KB1 shares 99.4% and 99.6% amino acid (aa) sequence identity with mouse and rat RPS6KB1, respectively.
Molecular Weight	68 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P23443
Gene Id	6198
Gene Name	RPS6KB1

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Ben-Sahra, I., Howell, J. J., Asara, J. M., Manning, B. D. Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. Science 339: 1323-1328, 2013. 2. Dorrello, N. V., Peschiaroli, A., Guardavaccaro, D., Colbu, N. H., Sherman, N. E., Pagano, M. S6K1- and beta-TRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314: 467-471, 2006. 3. Fingar, D. C., Salama, S., Tsou, C., Harlow, E., Blenis, J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev. 16: 1472-1487, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006385-1	A01475-3	-	100 ug	$370		Add to Cart
BHA21006385-2	A01475-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21006385-3	A01475-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006385-4	A01475-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006385-5	A01475-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006385-6	A01475-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006385-7	A01475-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006385-8	A01475-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21006385-9	A01475-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21006385-10	A01475-3-APC	APC	100 ug	$670		Add to Cart
BHA21006385-11	A01475-3-PE	PE	100 ug	$670		Add to Cart
BHA21006385-12	A01475-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006385-13	A01475-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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