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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NUP58 Antibody Picoband®

SKU : BHA21003714

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Mfr.No.	A09840, A09840-10ug, A09840-Biotin, A09840-Cy3, A09840-Dylight488, A09840-Dylight550, A09840-Dylight594, A09840-FITC, A09840-HRP, A09840-APC, A09840-PE, A09840-iFluor647, A09840-carrier-free
Alternative Names	interleukin 36, alpha
Background	This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alteate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NUP58 Antibody Picoband® catalog # A09840. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in tu activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in
Host	Rabbit
Immunogen Region	E.coli-derived human NUP58 recombinant protein (Position: R235-E438).
Isotype	Rabbit IgG
Molecular Weight	69 kDa
Reactivity	Human, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Interleukin-36 alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6
Tissue Specificity	Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9BVL2
Gene Id	9818
Gene Name	NUP58
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Chug, H., Trakhanov, S., Hulsmann, B. B., Pleiner, T., Gorlich, D. Crystal structure of the metazoan Nup62-Nup58-Nup54 nucleoporin complex. Science 350: 106-110, 2015. 2. Ishikawa, K., Nagase, T., Nakajima, D., Seki, N., Ohira, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 4: 307-313, 1997.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003714-1	A09840	-	100 ug	$370		Add to Cart
BHA21003714-2	A09840-10ug	Sample	10 ug	$99		Add to Cart
BHA21003714-3	A09840-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003714-4	A09840-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003714-5	A09840-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003714-6	A09840-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003714-7	A09840-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003714-8	A09840-FITC	FITC	100 ug	$570		Add to Cart
BHA21003714-9	A09840-HRP	HRP	100 ug	$570		Add to Cart
BHA21003714-10	A09840-APC	APC	100 ug	$670		Add to Cart
BHA21003714-11	A09840-PE	PE	100 ug	$670		Add to Cart
BHA21003714-12	A09840-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003714-13	A09840-carrier-free	carrier-free	100 ug	$370		Add to Cart

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