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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Myeloperoxidase/MPO Antibody Picoband®

SKU : BHA21007515

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Mfr.No.	PB9057, PB9057-10ug, PB9057-Biotin, PB9057-Cy3, PB9057-Dylight488, PB9057-Dylight550, PB9057-Dylight594, PB9057-FITC, PB9057-HRP, PB9057-APC, PB9057-PE, PB9057-iFluor647, PB9057-carrier-free
Alternative Names	Myeloperoxidase
Background	Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697 (A49-S745) amino acids with the molecular mass of 80KDa.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Myeloperoxidase/MPO Antibody Picoband® catalog # PB9057. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiol
Host	Rabbit
Immunogen Region	E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
Isotype	Rabbit IgG
Molecular Weight	60-65 kDa, 80-90 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Myeloperoxidase;MPO;1.11.2.2;Myeloperoxidase;89 kDa myeloperoxidase;84 kDa myeloperoxidase;Myeloperoxidase light chain;Myeloperoxidase heavy chain;MPO;
Tissue Specificity	Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions. .
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P05164
Gene Id	4353
Gene Name	MPO
Sequence	Belongs to the peroxidase family. XPO subfamily.
Subcellular Location	Lysosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Klebanoff, S. J. : Myeloperoxidase. Proc. Assoc. Am. Phys. 111: 383-389, 1999. 2. Murao, S.-I.; Stevens, F. J.; Ito, A.; Huberman, E. : Myeloperoxidase: a myeloid cell nuclear antigen with DNA-binding properties. Proc. Nat. Acad. Sci. 85: 1232-1236, 1988. 3. Nauseef, W. M.; Olsson, I.; Aljots, K. : Biosynthesis and processing of myeloperoxidase--a marker for myeloid cell differentiation. Europ. J. Haemat. 40: 97-110, 1988.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007515-1	PB9057	-	100 ug	$370		Add to Cart
BHA21007515-2	PB9057-10ug	Sample	10 ug	$99		Add to Cart
BHA21007515-3	PB9057-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007515-4	PB9057-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007515-5	PB9057-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007515-6	PB9057-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007515-7	PB9057-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007515-8	PB9057-FITC	FITC	100 ug	$570		Add to Cart
BHA21007515-9	PB9057-HRP	HRP	100 ug	$570		Add to Cart
BHA21007515-10	PB9057-APC	APC	100 ug	$670		Add to Cart
BHA21007515-11	PB9057-PE	PE	100 ug	$670		Add to Cart
BHA21007515-12	PB9057-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007515-13	PB9057-carrier-free	carrier-free	100 ug	$370		Add to Cart

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