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Home / Primary Antibodies / Monoclonal Antibodies

Anti-MSH2

SKU : BHA15100252

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Mfr.No.	AN743-5M
Clonality	Monoclonal
Description	MutS homologue 2 (MSH2) is a member of Mutator S (MutS) DNA mismatch repair protein family. MSH2 bind to DNA mismatches to initiate DNA repair by forming heterodimer complexes such as: MutS alpha (MSH2-MSH6) and MutS beta (MSH2-MSH3). MSH2 mutations are found in approximately 50% of inherited non polyposis colorectal carcinoma (HNPCC) (Lynch syndrome) cases. HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. Immunohistochemical analysis of MSH2 expression has been reported to be a practical and reliable method for the routine detection of the vast majority of MSI-H colorectal adenocarcinomas
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	SP46
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN743-5M	AN743-5M	6 mL	$319		Add to Cart
AN743-10M	AN743-10M	100 tests - i6000	$574		Add to Cart
AY743-50D	AY743-50D	50 tests - Xmatrx	$336		Add to Cart
AY743-YCD	AY743-YCD	160 tests - Xmatrx	$914		Add to Cart
NU743-UC	NU743-UC	1ml Conc	$438		Add to Cart
NU743-5UC	NU743-5UC	0.5ml Conc	$305		Add to Cart

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