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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Monoamine Oxidase A/MAOA Antibody Picoband®

SKU : BHA21006955

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Mfr.No.	PA1648, PA1648-10ug, PA1648-Biotin, PA1648-Cy3, PA1648-Dylight488, PA1648-Dylight550, PA1648-Dylight594, PA1648-FITC, PA1648-HRP, PA1648-APC, PA1648-PE, PA1648-iFluor647, PA1648-carrier-free
Alternative Names	Amine oxidase (flavin-containing) A
Background	MAOA (Monoamine oxidase A), also known as AMINE OXIDASE (FLAVIN-CONTAINING) A, is an enzyme that in humans is encoded by the MAO-A gene. MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3. MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Inhibition of MAOA prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Monoamine Oxidase A/MAOA Antibody catalog # PA1648. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines suc
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human MAOA.
Isotype	Rabbit IgG
Molecular Weight	65 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Amine oxidase (flavin-containing) A;1.4.3.4;Monoamine oxidase type A;MAO-A;MAOA;
Tissue Specificity	Heart, liver, duodenum, blood vessels and kidney.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P21397
Gene Name	MAOA
Sequence	Belongs to the flavin monoamine oxidase family.
Subcellular Location	Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Breakefield, X. O., Ozelius, L., Hsu, Y. P., Powell, J., Utterback, M., Gusella, J. F., Bruns, G. A. Gene for A form of human monoamine oxidase (MAOA) maps to Xp21-Xp11. (Abstract) Am. J. Hum. Genet. 41: A209 only, 1987.<br /><br />2. Brunner, H. G., Nelen, M., Breakefield, X. O., Ropers, H. H., van Oost, B. A. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A. Science 262: 578-580, 1993.<br /><br />3. PDB 2BXS; De Colibus L, Li M, Binda C, Lustig A, Edmondson DE, Mattevi A (September 2005). "Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B".<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006955-1	PA1648	-	100 ug	$370		Add to Cart
BHA21006955-2	PA1648-10ug	Sample	10 ug	$99		Add to Cart
BHA21006955-3	PA1648-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006955-4	PA1648-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006955-5	PA1648-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006955-6	PA1648-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006955-7	PA1648-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006955-8	PA1648-FITC	FITC	100 ug	$570		Add to Cart
BHA21006955-9	PA1648-HRP	HRP	100 ug	$570		Add to Cart
BHA21006955-10	PA1648-APC	APC	100 ug	$670		Add to Cart
BHA21006955-11	PA1648-PE	PE	100 ug	$670		Add to Cart
BHA21006955-12	PA1648-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006955-13	PA1648-carrier-free	carrier-free	100 ug	$370		Add to Cart

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