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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband®

SKU : BHA21001134

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Mfr.No.	A01065, A01065-10ug, A01065-Biotin, A01065-Cy3, A01065-Dylight488, A01065-Dylight550, A01065-Dylight594, A01065-FITC, A01065-HRP, A01065-APC, A01065-PE, A01065-iFluor647, A01065-carrier-free
Alternative Names	Methylmalonyl-CoA mutase, mitochondrial
Background	Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband® catalog # A01065. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human MUT, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	83 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Methylmalonyl-CoA mutase, mitochondrial;MCM;5.4.99.2 ;Methylmalonyl-CoA isomerase;MUT;
Tissue Specificity	T-cell specific.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P22033
Gene Id	4594
Gene Name	MUT
Subcellular Location	Mitochondrion matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Adjalla, C. E., Hosack, A. R., Gilfix, B. M., Lamothe, E., Sun, S., Chan, A., Evans, S., Matiaszuk, N. V., Rosenblatt, D. S. Seven novel mutations in mut methylmalonic aciduria. Hum. Mutat. 11: 270-274, 1998. <br /><br />2. Berger, I., Shaag, A., Anikster, Y., Baumgartner, E. R., Bar-Meir, M., Joseph, A., Elpeleg, O. N. Mutation analysis of the MCM gene in Israeli patients with mut(0) disease. Molec. Genet. Metab. 73: 107-110, 2001. <br /><br />3. Cavicchi, C., Donati, M. A., Funghini, S., la Marca, G., Malvagia, S., Ciani, F., Poggi, G. M., Pasquini, E., Zammarchi, E., Morrone, A. Genetic and biochemical approach to early prenatal diagnosis in a family with mut methylmalonic aciduria. Clin. Genet. 69: 72-76, 2006.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001134-1	A01065	100 ug	-	$370		Add to Cart
BHA21001134-2	A01065-10ug	10 ug	Sample	$99		Add to Cart
BHA21001134-3	A01065-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001134-4	A01065-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001134-5	A01065-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001134-6	A01065-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001134-7	A01065-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001134-8	A01065-FITC	100 ug	FITC	$570		Add to Cart
BHA21001134-9	A01065-HRP	100 ug	HRP	$570		Add to Cart
BHA21001134-10	A01065-APC	100 ug	APC	$670		Add to Cart
BHA21001134-11	A01065-PE	100 ug	PE	$670		Add to Cart
BHA21001134-12	A01065-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001134-13	A01065-carrier-free	100 ug	carrier-free	$370		Add to Cart

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