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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody Picoband®

SKU : BHA21006657

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Mfr.No.	PA1078, PA1078-10ug, PA1078-Biotin, PA1078-Cy3, PA1078-Dylight488, PA1078-Dylight550, PA1078-Dylight594, PA1078-FITC, PA1078-HRP, PA1078-APC, PA1078-PE, PA1078-iFluor647, PA1078-carrier-free
Alternative Names	Metalloproteinase inhibitor 4
Background	Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Metalloproteinase inhibitor 4 TIMP4 Antibody catalog # PA1078. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP4, different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	25 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Metalloproteinase inhibitor 4;Tissue inhibitor of metalloproteinases 4;TIMP-4;TIMP4;
Tissue Specificity	Abundant in heart and present at low levels in many other tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q99727
Gene Name	TIMP4
Sequence	Belongs to the protease inhibitor I35 (TIMP) family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>

Reference	1. "Entrez Gene: THPO TIMP4 (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor)".<br /><br />2. Olson TM, Hirohata S, Ye J, Leco K, Seldin MF, Apte SS (Sep 1998). "Cloning of the human tissue inhibitor of metalloproteinase-4 gene (TIMP4) and localization of the TIMP4 and Timp4 genes to human chromosome 3p25 and mouse chromosome 6, respectively". Genomics. 51 (1): 148151.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006657-1	PA1078	-	100 ug	$370		Add to Cart
BHA21006657-2	PA1078-10ug	Sample	10 ug	$99		Add to Cart
BHA21006657-3	PA1078-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006657-4	PA1078-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006657-5	PA1078-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006657-6	PA1078-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006657-7	PA1078-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006657-8	PA1078-FITC	FITC	100 ug	$570		Add to Cart
BHA21006657-9	PA1078-HRP	HRP	100 ug	$570		Add to Cart
BHA21006657-10	PA1078-APC	APC	100 ug	$670		Add to Cart
BHA21006657-11	PA1078-PE	PE	100 ug	$670		Add to Cart
BHA21006657-12	PA1078-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006657-13	PA1078-carrier-free	carrier-free	100 ug	$370		Add to Cart

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