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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody Picoband®

SKU : BHA21006762

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Mfr.No.	PA1385, PA1385-10ug, PA1385-Biotin, PA1385-Cy3, PA1385-Dylight488, PA1385-Dylight550, PA1385-Dylight594, PA1385-FITC, PA1385-HRP, PA1385-APC, PA1385-PE, PA1385-iFluor647, PA1385-carrier-free
Alternative Names	Metalloproteinase inhibitor 1
Background	TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Metalloproteinase inhibitor 1 TIMP1 Antibody catalog # PA1385. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP-1.
Isotype	Rabbit IgG
Molecular Weight	23 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Metalloproteinase inhibitor 1;Erythroid-potentiating activity;EPA;Fibroblast collagenase inhibitor;Collagenase inhibitor;Tissue inhibitor of metalloproteinases 1;TIMP-1;TIMP1;CLGI, TIMP;
Tissue Specificity	Detected in rheumatoid synovial fluid (at protein level). .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P01033
Gene Name	TIMP1
Sequence	Belongs to the protease inhibitor I35 (TIMP) family.
Subcellular Location	Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat <br>Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. TIMP1 TIMP metallopeptidase inhibitor 1"

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006762-1	PA1385	-	100 ug	$370		Add to Cart
BHA21006762-2	PA1385-10ug	Sample	10 ug	$99		Add to Cart
BHA21006762-3	PA1385-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006762-4	PA1385-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006762-5	PA1385-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006762-6	PA1385-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006762-7	PA1385-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006762-8	PA1385-FITC	FITC	100 ug	$570		Add to Cart
BHA21006762-9	PA1385-HRP	HRP	100 ug	$570		Add to Cart
BHA21006762-10	PA1385-APC	APC	100 ug	$670		Add to Cart
BHA21006762-11	PA1385-PE	PE	100 ug	$670		Add to Cart
BHA21006762-12	PA1385-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006762-13	PA1385-carrier-free	carrier-free	100 ug	$370		Add to Cart

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