JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-Metabotropic Glutamate Receptor 5/GRM5 Antibody Picoband®

SKU : BHA21002341

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	A01338-1, A01338-1-10ug, A01338-1-Biotin, A01338-1-Cy3, A01338-1-Dylight488, A01338-1-Dylight550, A01338-1-Dylight594, A01338-1-FITC, A01338-1-HRP, A01338-1-APC, A01338-1-PE, A01338-1-iFluor647, A01338-1-carrier-free
Alternative Names	glutamate metabotropic receptor 5
Background	Metabotropic glutamate receptor 5 is a G protein-coupled receptor that in humans is encoded by the GRM5 gene. It is mapped to 11q14.2-q14.3. This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Metabotropic Glutamate Receptor 5/GRM5 Antibody catalog # A01338-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinosi
Host	Rabbit
Immunogen Region	E.coli-derived human Metabotropic Glutamate Receptor 5/GRM5 recombinant protein (Position: E24-D560).
Isotype	Rabbit IgG
Molecular Weight	150 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Metabotropic glutamate receptor 5; mGluR5; GRM5; GPRC1E, MGLUR5
Tissue Specificity	Isoform 1 and isoform 2 are detected in bone marrow cells, spermatogonia and spermatocytes, but not in round spermatids, elongating spermatids and spermatozoa. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa, but not in spermatogonia and spermatocytes (at protein level). Isoform 1 is widely expressed and detected in fetal liver and bone marrow. Isoform 3 is detected in bone marrow cells enriched in hematopoietic stem cells.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P41594
Gene Id	2915
Gene Name	GRM5

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.5-1ug/ml, Mouse, Rat<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Minakami R, Katsuki F, Yamamoto T, Nakamura K, Sugiyama H (March 1994). "Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5". Biochemical and Biophysical Research Communications. 199 (3): 113643.<br /><br />2. Chen Y, Goudet C, Pin JP, Conn PJ (March 2008). "N-{4-Chloro-2-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors". Molecular Pharmacology. 73 (3): 90918. 3. Watkins JC, Jane DE (January 2006). "The glutamate story". British Joual of Pharmacology. 147 Suppl 1 (Suppl 1): S1008. doi:10.1038/sj.bjp.0706444.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002341-1	A01338-1	-	100 ug	$370		Add to Cart
BHA21002341-2	A01338-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21002341-3	A01338-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002341-4	A01338-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002341-5	A01338-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002341-6	A01338-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002341-7	A01338-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002341-8	A01338-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21002341-9	A01338-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21002341-10	A01338-1-APC	APC	100 ug	$670		Add to Cart
BHA21002341-11	A01338-1-PE	PE	100 ug	$670		Add to Cart
BHA21002341-12	A01338-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002341-13	A01338-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.