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Home / Primary Antibodies / IHC Antibodies

Anti-MAP2K2 Antibody BHA11300396

SKU : BHA11300396

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Mfr.No.	BS1226
Alternative Names	Dual specificity mitogen-activated protein kinase kinase 2 ; MAP kinase kinase 2 ; MAPKK 2 ; ERK activator kinase 2 ; MAPK/ERK kinase 2 ; MEK 2 ; MAP2K2 ; MEK-2 ; MKK2 ; PRKMK2
Categories	Primary Antibodies
Chromosome Location	19p13.3
Clonality	polyclonal
Description	MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids C-terminus of Human MEK-2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P36507
Uniprot	P36507
Weight	45 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: MEK2 (R388 )pAb detects endogenous levels of MEK2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IP

Description

WB ; IHC ; IP

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IP	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300396	BS1226	50µl	$190.44		Add to Cart
BHA11300396	BS1226	100µl	$294.44		Add to Cart

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