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Home / Primary Antibodies / Polyclonal Antibodies

Anti-LOXL1 Antibody Picoband®

SKU : BHA21000619

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Mfr.No.	PB9719, PB9719-10ug, PB9719-Biotin, PB9719-Cy3, PB9719-Dylight488, PB9719-Dylight550, PB9719-Dylight594, PB9719-FITC, PB9719-HRP, PB9719-APC, PB9719-PE, PB9719-iFluor647, PB9719-carrier-free
Alternative Names	Lysyl oxidase homolog 1
Background	Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-LOXL1 Antibody Picoband® catalog # PB9719. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Active on elastin and collagen substrates. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	63 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Lysyl oxidase homolog 1;1.4.3.-;Lysyl oxidase-like protein 1;LOL;LOXL1;LOXL;
Tissue Specificity	Expressed in ocular tissues including the iris, ciliary body, lens and optic nerve. Not detected in the retina. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q08397
Gene Id	4016
Gene Name	LOXL1
Subcellular Location	Secreted, extracellular space .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25". The Joual of Biological Chemistry 268 (25): 184357. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. (United States) 36 (2): 17882. 3. "Entrez Gene: LOXL1 lysyl oxidase-like 1".

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000619-1	PB9719	100 ug	-	$370		Add to Cart
BHA21000619-2	PB9719-10ug	10 ug	Sample	$99		Add to Cart
BHA21000619-3	PB9719-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000619-4	PB9719-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000619-5	PB9719-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000619-6	PB9719-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000619-7	PB9719-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000619-8	PB9719-FITC	100 ug	FITC	$570		Add to Cart
BHA21000619-9	PB9719-HRP	100 ug	HRP	$570		Add to Cart
BHA21000619-10	PB9719-APC	100 ug	APC	$670		Add to Cart
BHA21000619-11	PB9719-PE	100 ug	PE	$670		Add to Cart
BHA21000619-12	PB9719-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000619-13	PB9719-carrier-free	100 ug	carrier-free	$370		Add to Cart

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