Ki-67 is a nuclear, non-histone protein that is expressed only during active phases of the cell cycle (G1, S, G2 and M), but not in the resting phases (G0 and G1 early phase). Although the antigen has also been associated with ribosomal RNA transcription, it is strongly linked to cell proliferation and has thus been indicated as an effective marker in grading the proliferation rate of tumours, including those of the brain, breast, cervix, and prostate.
Host
Rabbit
Isotype
IgG, kappa (Rab)
Species
Human
Clone No
IHC167
Buffer
Tris Buffer pH7.6 with BSA, and sodium azide as preservative