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Home / Primary Antibodies / Recombinant Antibodies

Anti-KDM5B Antibody BHA11305692

SKU : BHA11305692

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Mfr.No.	BS70906
Alternative Names	Lysine-specific demethylase 5B ; Cancer/testis antigen 31 ; CT31 ; PLU-1 ; RBP2-H1 ; JARID1B ; PLU1 ; RBBP2H1
Antigen	KDM5B
Categories	Primary Antibodies
Chromosome Location	1q32.1
Clonality	polyclonal
Description	Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
Host	Rabbit
Immunogen	Recombinant protein of human KDM5B.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UGL1
Uniprot	Q9UGL1
Weight	176 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: KDM5B polyclonal antibody detects endogenous levels of KDM5B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11305692	BS70906	50µl	$234.89		Add to Cart
BHA11305692	BS70906	100µl	$368.22		Add to Cart

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