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Home / Primary Antibodies / IHC Antibodies

Anti-KDELR3 Antibody BHA11301789

SKU : BHA11301789

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Mfr.No.	BS3124
Alternative Names	ER lumen protein retaining receptor 3 ; KDEL endoplasmic reticulum protein retention receptor 3 ; Short name=KDEL receptor 3 ; KDELR3
Categories	Primary Antibodies
Chromosome Location	22q13.1
Clonality	polyclonal
Description	Soluble proteins in the endoplasmic reticulum (ER) contain a specific carboxy terminal sequence KDEL (Lys-Asp-Glu-Leu), and include the coat proteins required for vesicle budding from the ER, proteins that form retrogradevesicles on post-ER compartments, and integral membrane proteins that target vesicles to their correct destination. The retention of these soluble proteins in the ER depends on the interaction of the KDEL sequence with the corresponding KDEL receptor, also designated ERD2, in the Golgi apparatus.When KDEL proteins reach the Golgi complex, they are recognized by the KDEL receptor and transported retrograde in COPI-coated vesicles back to the ER. The small GTPase ADP-ribosylation factor 1 (ARF1), a regulator of vesicle transport, interacts with the KDEL receptor.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 71-120 of Human KDEL Receptor 3.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O43731
Uniprot	O43731
Weight	25 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: KDEL Receptor 3 (L95) polyclonal antibody detects endogenous levels of KDEL Receptor 3 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301789	BS3124	50µl	$190.44		Add to Cart
BHA11301789	BS3124	100µl	$294.44		Add to Cart

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