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Home / Primary Antibodies / Monoclonal Antibodies

Anti-IRBIT/AHCYL1 Antibody Picoband® (monoclonal, 2E7D9)

SKU : BHA21004823

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Mfr.No.	M08908, M08908-10ug, M08908-Biotin, M08908-Cy3, M08908-Dylight488, M08908-Dylight550, M08908-Dylight594, M08908-FITC, M08908-HRP, M08908-APC, M08908-PE, M08908-iFluor647, M08908-carrier-free
Alternative Names	chaperonin containing TCP1 subunit 3
Background	Putative adenosylhomocysteinase 2 is an enzyme that in humans is encoded by the AHCYL1 gene. The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IRBIT/AHCYL1 Antibody Picoband® (monoclonal, 2E7D9) catalog # M08908. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vi
Host	Mouse
Immunogen Region	E.coli-derived human IRBIT/AHCYL1 recombinant protein (Position: E14-K57).
Isotype	IgG1
Molecular Weight	59 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	T-complex protein 1 subunit gamma; TCP-1-gamma; CCT-gamma; hTRiC5; CCT3; CCTG; TRIC5
Tissue Specificity	Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	O43865
Gene Id	10768
Gene Name	AHCYL1
Clone No	Clone: 2E7D9
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Ando, H., Mizutani, A., Kiefer, H., Tsuzurugi, D., Michikawa, T., Mikoshiba, K. IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor. Molec. Cell 22: 795-806, 2006. 2. Ando, H., Mizutani, A., Matsu-ura, T., Mikoshiba, K. IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor. J. Biol. Chem. 278: 10602-10612, 2003. 3. Ando, H., Mizutani, A., Mikoshiba, K. An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage. J. Neurochem. 109: 539-550, 2009.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004823-1	M08908	-	100 ug	$370		Add to Cart
BHA21004823-2	M08908-10ug	Sample	10 ug	$99		Add to Cart
BHA21004823-3	M08908-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004823-4	M08908-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004823-5	M08908-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004823-6	M08908-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004823-7	M08908-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004823-8	M08908-FITC	FITC	100 ug	$570		Add to Cart
BHA21004823-9	M08908-HRP	HRP	100 ug	$570		Add to Cart
BHA21004823-10	M08908-APC	APC	100 ug	$670		Add to Cart
BHA21004823-11	M08908-PE	PE	100 ug	$670		Add to Cart
BHA21004823-12	M08908-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004823-13	M08908-carrier-free	carrier-free	100 ug	$370		Add to Cart

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