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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-3 IL3 Antibody Picoband®

SKU : BHA21006782

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Mfr.No.	PA1423, PA1423-10ug, PA1423-Biotin, PA1423-Cy3, PA1423-Dylight488, PA1423-Dylight550, PA1423-Dylight594, PA1423-FITC, PA1423-HRP, PA1423-APC, PA1423-PE, PA1423-iFluor647, PA1423-carrier-free
Alternative Names	Interleukin-3
Background	The gene IL-3 encodes interleukin 3, a hematopoietic colony-stimulating factor (CSF) that is capable of supporting the proliferation of a broad range of hematopoietic cell types.1 Interleukin-3 (IL-3), a protein of 140 amino acids, is chemically synthesized by means of an automated peptide synthesizer and is shown to have the biological activities attributed to native IL-3.2 The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide.3 The mouse IL 3 gene is located on chromosome 11.4 The human gene encoding IL 3 is tandemly arrayed on the long arm of chromosome 5.5 The standard product used in this kit is recombinant human IL-3, consisting of 133 amino acids with the molecular mass of 15KDa.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-3 IL3 Antibody catalog # PA1423. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human IL-3.
Isotype	Rabbit IgG
Molecular Weight	15 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-3;IL-3;Hematopoietic growth factor;Mast cell growth factor;MCGF;Multipotential colony-stimulating factor;P-cell-stimulating factor;IL3;
Tissue Specificity	Activated T-cells, mast cells, natural killer cells.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P08700
Gene Name	IL3
Sequence	Belongs to the IL-3 family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Le Beau, M. M.; Epstein, N. D.; O'Brien, S. J.; Nienhuis, A. W.; Yang, Y.-C.; Clark, S. C.; Rowley, J. D. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q. Proc. Nat. Acad. Sci. 84: 5913-5917, 1987.<br /><br />2. Clark-Lewis, I.; Aebersold, R.; Ziltener, H.; Schrader, J. W.; Hood, L. E.; Kent, S. B. H. Automated chemical synthesis of a protein growth factor for hemopoietic cells, interleukin-3. Science 231: 134-139, 1986.<br /><br />3. Fung, M. C.; Hapel, A. J.; Ymer, S.; Cohen, D. R.; Johnson, R. M.; Campbell, H. D.; Young, I. G. Molecular cloning of cDNA for murine interleukin-3. Nature 307: 233-237, 1984.<br /><br />4. Ihle, J. N.; Silver, J.; Kozak, C. A. Genetic mapping of the mouse interleukin 3 gene to chromosome 11. J. Immun. 138: 3051-3054, 1987.<br /><br />5. Yang, Y.-C.; Kovacic, S.; Kriz, R.; Wolf, S.; Clark, S. C.; Wellems, T. E.; Nienhuis, A.; Epstein, N. The human genes for GM-CSF and IL3 are closely linked in tandem on chromosome 5. Blood 71: 958-961, 1988.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006782-1	PA1423	-	100 ug	$370		Add to Cart
BHA21006782-2	PA1423-10ug	Sample	10 ug	$99		Add to Cart
BHA21006782-3	PA1423-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006782-4	PA1423-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006782-5	PA1423-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006782-6	PA1423-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006782-7	PA1423-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006782-8	PA1423-FITC	FITC	100 ug	$570		Add to Cart
BHA21006782-9	PA1423-HRP	HRP	100 ug	$570		Add to Cart
BHA21006782-10	PA1423-APC	APC	100 ug	$670		Add to Cart
BHA21006782-11	PA1423-PE	PE	100 ug	$670		Add to Cart
BHA21006782-12	PA1423-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006782-13	PA1423-carrier-free	carrier-free	100 ug	$370		Add to Cart

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