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Home / Primary Antibodies / IHC Antibodies

Anti-INSR Antibody BHA11302180

SKU : BHA11302180

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Mfr.No.	BS3744
Alternative Names	Insulin receptor ; IR ; CD220 ; INSR
Antigen	INSR
Categories	Primary Antibodies
Chromosome Location	19p13.2
Clonality	polyclonal
Description	The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular β subunit and an extracellular α subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 1341-1390 of Human Leu-1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P06213
Uniprot	P06213
Weight	95, 156 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Insulin Receptor (K1368) polyclonal antibody detects endogenous levels of Insulin Receptor protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302180	BS3744	50µl	$190.44		Add to Cart
BHA11302180	BS3744	100µl	$294.44		Add to Cart

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