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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IL2 Receptor beta/IL2RB Antibody Picoband®

SKU : BHA21006929

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Mfr.No.	PA1615, PA1615-10ug, PA1615-Biotin, PA1615-Cy3, PA1615-Dylight488, PA1615-Dylight550, PA1615-Dylight594, PA1615-FITC, PA1615-HRP, PA1615-APC, PA1615-PE, PA1615-iFluor647, PA1615-carrier-free
Alternative Names	Interleukin-2 receptor subunit beta
Background	IL2RB (INTERLEUKIN 2 RECEPTOR, BETA),also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-IL2 Receptor beta/IL2RB Antibody catalog # PA1615. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human IL2RB.
Isotype	Rabbit IgG
Molecular Weight	75 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;p75;CD122;IL2RB;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P14784
Gene Name	IL2RB
Sequence	Belongs to the type I cytokine receptor family. Type 4 subfamily.
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Campbell, H. D., Webb, G. C., Kono, T., Taniguchi, T., Ford, J. H., Young, I. G. Assignment of the interleukin-2 receptor beta chain gene (Il-2rb) to band E on mouse chromosome 15. Genomics 12: 179-180, 1992.<br /><br />2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010. <br /><br />3. Yamashita, Yuki; Kojima Katsuhiko, Tsukahara Tomonori, Agawa Hideyuki, Yamada Koichiro, Amano Yuji, Kurotori Naoki, Tanaka Nobuyuki, Sugamura Kazuo, Takeshita Toshikazu (May. 2008). "Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain". J. Cell. Sci. (England) 121 (Pt 10): 172738. doi:10.1242/jcs.024455. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006929-1	PA1615	-	100 ug	$370		Add to Cart
BHA21006929-2	PA1615-10ug	Sample	10 ug	$99		Add to Cart
BHA21006929-3	PA1615-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006929-4	PA1615-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006929-5	PA1615-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006929-6	PA1615-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006929-7	PA1615-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006929-8	PA1615-FITC	FITC	100 ug	$570		Add to Cart
BHA21006929-9	PA1615-HRP	HRP	100 ug	$570		Add to Cart
BHA21006929-10	PA1615-APC	APC	100 ug	$670		Add to Cart
BHA21006929-11	PA1615-PE	PE	100 ug	$670		Add to Cart
BHA21006929-12	PA1615-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006929-13	PA1615-carrier-free	carrier-free	100 ug	$370		Add to Cart

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