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Home / Primary Antibodies / Polyclonal Antibodies

Anti-IKKi/IKKe/IKBKE Antibody Picoband®

SKU : BHA21002973

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Mfr.No.	A01816-2, A01816-2-10ug, A01816-2-Biotin, A01816-2-Cy3, A01816-2-Dylight488, A01816-2-Dylight550, A01816-2-Dylight594, A01816-2-FITC, A01816-2-HRP, A01816-2-APC, A01816-2-PE, A01816-2-iFluor647, A01816-2-carrier-free
Alternative Names	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Background	Inhibitor of nuclear factor kappa-B kinase subunit epsilon also known as I-kappa-B kinase epsilon or IKK-epsilon is an enzyme that in humans is encoded by the IKBKE gene. IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell line.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-IKKi/IKKe/IKBKE Antibody Picoband® catalog # A01816-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney (PubMed:19903818). Contributes to the regulation of the membrane potentia
Host	Rabbit
Immunogen Region	E.coli-derived human IKKi/IKKe/IKBKE recombinant protein (Position: Q318-V716).
Isotype	Rabbit IgG
Molecular Weight	80 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Potassium voltage-gated channel subfamily A member 1; Voltage-gated K (+) channel HuKI
Tissue Specificity	Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297). Detected in the islet of Langerhans (PubMed:21483673).
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q14164
Gene Id	9641
Gene Name	IKBKE
Subcellular Location	Cell membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5ug/ml, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Chiang, S.-H., Bazuine, M., Lumeng, C. N., Geletka, L. M., Mowers, J., White, N. M., Ma, J.-T., Zhou, J., Qi, N., Westcott, D., Delproposto, J. B., Blackwell, T. S., Yull, F. E., Saltiel, A. R. The protein kinase IKK-epsilon regulates energy balance in obese mice. Cell 138: 961-975, 2009. <br /><br />2. Hutti, J. E., Shen, R. R., Abbott, D. W., Zhou, A. Y., Sprott, K. M., Asara, J. M., Hahn, W. C., Cantley, L. C. Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKK-epsilon promotes cell transformation. Molec. Cell 34: 461-472, 2009. <br /><br />3. Nagase, T., Seki, N., Tanaka, A., Ishikawa, K., Nomura, N. Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2: 167-174, 1995.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002973-1	A01816-2	-	100 ug	$370		Add to Cart
BHA21002973-2	A01816-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002973-3	A01816-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002973-4	A01816-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002973-5	A01816-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002973-6	A01816-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002973-7	A01816-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002973-8	A01816-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002973-9	A01816-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002973-10	A01816-2-APC	APC	100 ug	$670		Add to Cart
BHA21002973-11	A01816-2-PE	PE	100 ug	$670		Add to Cart
BHA21002973-12	A01816-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002973-13	A01816-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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