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Home / Primary Antibodies / Polyclonal Antibodies

Anti-ICAM1 Antibody Picoband®

SKU : BHA21001510

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Mfr.No.	A00171, A00171-10ug, A00171-Biotin, A00171-Cy3, A00171-Dylight488, A00171-Dylight550, A00171-Dylight594, A00171-FITC, A00171-HRP, A00171-APC, A00171-PE, A00171-iFluor647, A00171-carrier-free
Alternative Names	intercellular adhesion molecule 1
Background	CD54, also known as ICAM-1. Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-ICAM1 Antibody Picoband® catalog # A00171. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Host	Rabbit
Immunogen Region	E. coli-derived human ICAM1 recombinant protein (Position: Q28-R268).
Isotype	Rabbit IgG
Molecular Weight	90 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Intercellular adhesion molecule 1; ICAM-1; Major group rhinovirus receptor; CD54; ICAM1
Tissue Specificity	Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P05362
Gene Id	3383
Gene Name	ICAM1
Subcellular Location	Membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Ballantyne, C. M.; Kozak, C. A.; O'Brien, W. E.; Beaudet, A. L. : Assignment of the gene for intercellular adhesion molecule-1 (Icam-1) to proximal mouse chromosome 9. Genomics 9: 547-550, 1991. <br /><br />2. Greve, J. M.; Davis, G.; Meyer, A. M.; Forte, C. P.; Yost, S. C.; Marlor, C. W.; Kamarck, M. E.; McClelland, A. : The major human rhinovirus receptor is ICAM-1. Cell 56: 839-847, 1989. <br /><br />3. Prieto, J.; Takei, F.; Gendelman, R.; Christenson, B.; Biberfeld, P.; Patarroyo, M. : MALA-2, mouse homologue of human adhesion molecule ICAM-1 (CD54). Europ. J. Immun. 19: 1551-1557, 1989.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001510-1	A00171	100 ug	-	$370		Add to Cart
BHA21001510-2	A00171-10ug	10 ug	Sample	$99		Add to Cart
BHA21001510-3	A00171-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001510-4	A00171-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001510-5	A00171-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001510-6	A00171-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001510-7	A00171-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001510-8	A00171-FITC	100 ug	FITC	$570		Add to Cart
BHA21001510-9	A00171-HRP	100 ug	HRP	$570		Add to Cart
BHA21001510-10	A00171-APC	100 ug	APC	$670		Add to Cart
BHA21001510-11	A00171-PE	100 ug	PE	$670		Add to Cart
BHA21001510-12	A00171-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001510-13	A00171-carrier-free	100 ug	carrier-free	$370		Add to Cart

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