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Home / Primary Antibodies / IHC Antibodies

Anti-HTR2C Antibody BHA11301583

SKU : BHA11301583

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Mfr.No.	BS2766
Alternative Names	5-hydroxytryptamine receptor 2C ; 5-HT-2C ; 5-HT2C ; 5-HTR2C ; 5-hydroxytryptamine receptor 1C ; 5-HT-1C ; 5-HT1C ; Serotonin receptor 2C
Antigen	HTR2C
Categories	Primary Antibodies
Chromosome Location	Xq23
Clonality	polyclonal
Description	In the CNS, Serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G proteincoupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to Serotonin. SR-2A has a specific role in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and adult cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 400-450 of Human SR-2C.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P28335
Uniprot	P28335
Weight	55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: SR-2C (Q437) polyclonal antibody detects endogenous levels of SR-2C protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301583	BS2766	50µl	$190.44		Add to Cart
BHA11301583	BS2766	100µl	$294.44		Add to Cart

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