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Home / Primary Antibodies / Polyclonal Antibodies

Anti-HSPA2 Antibody Picoband®

SKU : BHA21007081

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Mfr.No.	PA1814, PA1814-10ug, PA1814-Biotin, PA1814-Cy3, PA1814-Dylight488, PA1814-Dylight550, PA1814-Dylight594, PA1814-FITC, PA1814-HRP, PA1814-APC, PA1814-PE, PA1814-iFluor647, PA1814-carrier-free
Alternative Names	Heat shock-related 70 kDa protein 2
Background	HSPA2 (heat shock 70kDa protein 2) also known as HEAT-SHOCK PROTEIN, 70-KD, 2, HSP70-2, HEAT-SHOCK PROTEIN, 70-KD, 3 or HSP70-3. Analysis of the sequence indicated that HSPA2 is the human homolog of the murine Hsp70-2 gene, with 91.7% identity in the nucleotide coding sequence and 98.2% in the corresponding amino acid sequence.HSPA2 has less amino acid homology to the other members of the human HSP70 gene family. HSPA2 is constitutively expressed in most tissues, with very high levels in testis and skeletal muscle. The HSPA2 gene is located on chromosome 14q22-q24. Immunohistochemical analysis detected weak expression of HSPA2 in spermatocytes and stronger expression in spermatids and in the tail of mature sperm. HSPA2 may be critical to sperm maturation through its role as a protein chaperone.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-HSPA2 Antibody catalog # PA1814. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes throu
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human HSPA2, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Heat shock-related 70 kDa protein 2;Heat shock 70 kDa protein 2;HSPA2;
Tissue Specificity	HSPA1B is testis-specific.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P54652
Gene Name	HSPA2
Sequence	Belongs to the heat shock protein 70 family.
Subcellular Location	Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Bonnycastle, L. L. C., Yu, C.-E., Hunt, C. R., Trask, B. J., Clancy, K. P., Weber, J. L., Patterson, D., Schellenberg, G. D. Cloning, sequencing, and mapping of the human chromosome 14 heat shock protein gene (HSPA2). Genomics 23: 85-93, 1994.<br /><br />2. Dix, D. J., Allen, J. W., Collins, B. W., Mori, C., Nakamura, N., Poorman-Allen, P., Goulding, E. H., Eddy, E. M. Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility. Proc. Nat. Acad. Sci. 93: 3264-3268, 1996.<br /><br />3. Hunt, C. R., Gasser, D. L., Chaplin, D. D., Pierce, J. C., Kozak, C. A. Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t and Grp78. Genomics 16: 193-198, 1993.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007081-1	PA1814	-	100 ug	$370		Add to Cart
BHA21007081-2	PA1814-10ug	Sample	10 ug	$99		Add to Cart
BHA21007081-3	PA1814-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007081-4	PA1814-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007081-5	PA1814-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007081-6	PA1814-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007081-7	PA1814-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007081-8	PA1814-FITC	FITC	100 ug	$570		Add to Cart
BHA21007081-9	PA1814-HRP	HRP	100 ug	$570		Add to Cart
BHA21007081-10	PA1814-APC	APC	100 ug	$670		Add to Cart
BHA21007081-11	PA1814-PE	PE	100 ug	$670		Add to Cart
BHA21007081-12	PA1814-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007081-13	PA1814-carrier-free	carrier-free	100 ug	$370		Add to Cart

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