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Home / Primary Antibodies / IHC Antibodies

Anti-H2BFS Antibody BHA11300807

SKU : BHA11300807

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Mfr.No.	BS1657
Alternative Names	Histone H2B type F-S ; Histone H2B.s ; H2B/s ; H2BFS
Categories	Primary Antibodies
Chromosome Location	21q22.3
Clonality	polyclonal
Description	Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which consists of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids N-terminus of Human Histone H2B.
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P57053
Uniprot	P57053
Weight	14 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Histone H2B (K5) polyclonal antibody detects endogenous levels of Histone H2B protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300807	BS1657	50µl	$190.44		Add to Cart
BHA11300807	BS1657	100µl	$294.44		Add to Cart

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