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Home / Primary Antibodies / IHC Antibodies

Anti-H2AFX Antibody BHA11301700

SKU : BHA11301700

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Mfr.No.	BS2984
Alternative Names	Histone H2AX ; H2a/x ; Histone H2A.X ; H2AFX ; H2AX
Categories	Primary Antibodies
Chromosome Location	11q23.3
Clonality	polyclonal
Description	H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 100-150 of Human Histone H2A.X.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P16104
Uniprot	P16104
Weight	15 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Histone H2A.X (S130) polyclonal antibody detects endogenous levels of Histone H2A.X protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301700	BS2984	50µl	$190.44		Add to Cart
BHA11301700	BS2984	100µl	$294.44		Add to Cart

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