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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GSTA1/A2/A3/A4/A5 Antibody Picoband®

SKU : BHA21001313

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Mfr.No.	A01462-1, A01462-1-10ug, A01462-1-Biotin, A01462-1-Cy3, A01462-1-Dylight488, A01462-1-Dylight550, A01462-1-Dylight594, A01462-1-FITC, A01462-1-HRP, A01462-1-APC, A01462-1-PE, A01462-1-iFluor647, A01462-1-carrier-free
Alternative Names	glutathione S-transferase alpha 1/2/3/4/5
Background	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GSTA1/A2/A3/A4/A5 Antibody Picoband® catalog # A01462-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Host	Rabbit
Immunogen Region	E. coli-derived human GSTA1/A2/A3/A4/A5 recombinant protein (Position: A2-F222).
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutathione S-transferase A1; 2.5.1.18; GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1; Glutathione S-transferase A1, N-terminally processed; GSTA1;
Tissue Specificity	Liver.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	GSTA1: P08263
Gene Id	2938/2939/2940/2941/221357
Gene Name	GSTA1
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> ELISA (Cap), 1-5ug/ml<br>

Reference	1. "Entrez Gene: GSTA2 glutathione S-transferase A2".<br /><br />2. Röhrdanz E, Nguyen T, Pickett CB (1992). "Isolation and characterization of the human glutathione S-transferase A2 subunit gene.". Arch. Biochem. Biophys. 298 (2): 74752.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001313-1	A01462-1	100 ug	-	$370		Add to Cart
BHA21001313-2	A01462-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001313-3	A01462-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001313-4	A01462-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001313-5	A01462-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001313-6	A01462-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001313-7	A01462-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001313-8	A01462-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001313-9	A01462-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001313-10	A01462-1-APC	100 ug	APC	$670		Add to Cart
BHA21001313-11	A01462-1-PE	100 ug	PE	$670		Add to Cart
BHA21001313-12	A01462-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001313-13	A01462-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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