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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GRO gamma/CXCL3 Antibody Picoband®

SKU : BHA21000842

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Mfr.No.	PB9941, PB9941-10ug, PB9941-Biotin, PB9941-Cy3, PB9941-Dylight488, PB9941-Dylight550, PB9941-Dylight594, PB9941-FITC, PB9941-HRP, PB9941-APC, PB9941-PE, PB9941-iFluor647, PB9941-carrier-free
Alternative Names	C-X-C motif chemokine 3
Background	Chemokine (C-X-C motif) ligand 3 (CXCL3), also known as GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b), is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the inteal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-GRO gamma/CXCL3 Antibody Picoband® catalog # PB9941. Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. .
Host	Rabbit
Immunogen Region	E. coli-derived mouse GRO gamma recombinant protein (Position: S32-S100). Mouse GRO gamma shares 60.6% and 90.6% amino acid (aa) sequence identity with human and rat GRO gamma, respectively.
Isotype	Rabbit IgG
Molecular Weight	25 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	C-X-C motif chemokine 3;Dendritic cell inflammatory protein 1 ;Cxcl3 ;Dcip1 , Gm1960 ;
Tissue Specificity	Expressed in eye lens. .
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q6W5C0
Gene Id	330122
Gene Name	CXCL3
Subcellular Location	Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	ELISA, 0.1-0.5ug/ml, - Weste blot, 0.1-0.5ug/ml, Mouse

Reference	1. Ahuja SK, Murphy PM (August 1996). "The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor". J. Biol. Chem. 271 (34): 2054550. 2. Farioli-Vecchioli S, Cinà I, Ceccarelli M, Micheli L, Leonardi L, Ciotti MT, De Bardi M, Di Rocco C, Pallini R, Cavallaro S, Tirone F (October 2012). "Tis21 knock-out enhances the frequency of medulloblastoma in patched1 heterozygous mice by inhibiting the cxcl3-dependent migration of cerebellar neurons". The Joual of neuroscience : the official joual of the Society for Neuroscience 32 (44): 1554715564. 3. Smith DF, Galkina E, Ley K, Huo Y (November 2005). "GRO family chemokines are specialized for monocyte arrest from flow". Am. J. Physiol. Heart Circ. Physiol. 289 (5): H197684.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000842-1	PB9941	100 ug	-	$370		Add to Cart
BHA21000842-2	PB9941-10ug	10 ug	Sample	$99		Add to Cart
BHA21000842-3	PB9941-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000842-4	PB9941-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000842-5	PB9941-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000842-6	PB9941-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000842-7	PB9941-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000842-8	PB9941-FITC	100 ug	FITC	$570		Add to Cart
BHA21000842-9	PB9941-HRP	100 ug	HRP	$570		Add to Cart
BHA21000842-10	PB9941-APC	100 ug	APC	$670		Add to Cart
BHA21000842-11	PB9941-PE	100 ug	PE	$670		Add to Cart
BHA21000842-12	PB9941-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000842-13	PB9941-carrier-free	100 ug	carrier-free	$370		Add to Cart

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