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Home / Primary Antibodies / IHC Antibodies

Anti-GPR119 Antibody BHA11301488

SKU : BHA11301488

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Mfr.No.	BS2606
Alternative Names	Glucose-dependent insulinotropic receptor ; G-protein coupled receptor 119
Antigen	GPR119
Categories	Primary Antibodies
Chromosome Location	Xq26.1
Clonality	polyclonal
Description	G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intra cellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane- spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR119 is a 335 amino acid protein that is mainly expressed in the pancreas. It is an endogenous receptor for lysophosphatidylcholine (LPC), which is is a lipid mediator involved in insulin secretion from pancreatic  cells. GPR119 may participate in this insulin secretion, suggesting that it may be potential target for new anti-diabetic drugs.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 190-240 of Human GPR119.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q8TDV5
Uniprot	Q8TDV5
Weight	37 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: GPR119 (V227) polyclonal antibody detects endogenous levels of GPR119 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301488	BS2606	50µl	$190.44		Add to Cart
BHA11301488	BS2606	100µl	$294.44		Add to Cart

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