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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband®

SKU : BHA21000108

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Mfr.No.	PB9198, PB9198-10ug, PB9198-Biotin, PB9198-Cy3, PB9198-Dylight488, PB9198-Dylight550, PB9198-Dylight594, PB9198-FITC, PB9198-HRP, PB9198-APC, PB9198-PE, PB9198-iFluor647, PB9198-carrier-free
Alternative Names	Glucose-6-phosphate 1-dehydrogenase
Background	Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband® catalog # PB9198. Tested in WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates f
Host	Rabbit
Immunogen Region	E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.
Isotype	Rabbit IgG
Molecular Weight	59 kDa
Reactivity	Human, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glucose-6-phosphate 1-dehydrogenase;G6PD;1.1.1.49;G6PD;
Tissue Specificity	Isoform Long is found in lymphoblasts, granulocytes and sperm.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P11413
Gene Id	2539
Gene Name	G6PD
Sequence	Belongs to the glucose-6-phosphate dehydrogenase family.
Subcellular Location	Cytoplasm, cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse

Reference	1. Aster J, Kumar V, Robbins SL, Abbas AK, Fausto N, Cotran RS (2010). Robbins and Cotran pathologic basis of disease. Saunders/Elsevier. pp. Kindle Locations 3334033341. 2. Takizawa, T., Huang, I.-Y., Ikuta, T., Yoshida, A. Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning. Proc. Nat. Acad. Sci. 83: 4157-4161, 1986.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000108-1	PB9198	100 ug	-	$370		Add to Cart
BHA21000108-2	PB9198-10ug	10 ug	Sample	$99		Add to Cart
BHA21000108-3	PB9198-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000108-4	PB9198-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000108-5	PB9198-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000108-6	PB9198-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000108-7	PB9198-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000108-8	PB9198-FITC	100 ug	FITC	$570		Add to Cart
BHA21000108-9	PB9198-HRP	100 ug	HRP	$570		Add to Cart
BHA21000108-10	PB9198-APC	100 ug	APC	$670		Add to Cart
BHA21000108-11	PB9198-PE	100 ug	PE	$670		Add to Cart
BHA21000108-12	PB9198-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000108-13	PB9198-carrier-free	100 ug	carrier-free	$370		Add to Cart

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